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Published on: February 22, 2016

In preprints: toward a holistic lineage-tracing map of mammalian embryogenesis

Yingying Chen1, Xianfa Yang1

  • 1Guangzhou National Laboratory, Guangzhou International Bio Island, Guangzhou 510000, Guangdong Province, China.

Development (Cambridge, England)
|June 29, 2026
PubMed
Abstract

No abstract available in PubMed .

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Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata will form...