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Published on: March 19, 2020

Functionalized Pyridine-Based Iron(II) Complexes: Synthesis, Structural Characteristics and Catalytic Activity in

Gayetri Sarkar¹, Agnishwar Mangal¹, Souvik Chatterjee¹

¹Department of Chemistry, University of North Bengal, Darjeeling, India.

Chemistry, an Asian Journal

|June 29, 2026

Summary

This summary is machine-generated.

Four new iron complexes catalyze the selective oxidation of alcohols to aldehydes. Complex 1, featuring electron-rich ligands, shows superior efficiency and broad substrate scope in organic synthesis.

Keywords:

alcohol oxidation iron‐oxo species metaperiodate oxidant pyridine‐containing ligands rebound mechanism

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Syntheses, Crystallization, and Spectroscopic Characterization of 3,5-Lutidine N-Oxide Dehydrate

Syntheses, Crystallization, and Spectroscopic Characterization of 3,5-Lutidine N-Oxide Dehydrate

Published on: April 24, 2018

Area of Science:

Inorganic Chemistry
Organic Synthesis
Catalysis

Background:

Selective oxidation of alcohols to aldehydes is crucial in organic synthesis.
Development of efficient and selective catalysts is an ongoing research area.
Iron complexes offer a sustainable and cost-effective alternative to precious metal catalysts.

Purpose of the Study:

To synthesize and characterize novel iron complexes for catalytic applications.
To investigate the catalytic activity of these complexes in the selective oxidation of alcohols.
To elucidate the structure-activity relationship and reaction mechanism.

Main Methods:

Synthesis of four novel iron complexes (1-4) using functionalized bipyridine, phenanthroline, and pyridine-imidazole ligands.
Structural characterization using X-ray crystallography and spectroscopic techniques.
Evaluation of catalytic activity in alcohol oxidation using sodium periodate (NaIO4) as the terminal oxidant.

Main Results:

All synthesized iron complexes feature Fe(II) centers stabilized by various noncovalent interactions.
Complex 1, an electron-rich variant, exhibited superior catalytic performance, achieving high yields of aldehydes from diverse alcohols.
The catalytic system demonstrated excellent functional group tolerance and selectivity, preventing overoxidation.

Conclusions:

The newly developed iron complexes, particularly complex 1, are highly effective catalysts for the selective oxidation of alcohols to aldehydes.
The study provides insights into the role of ligand design and noncovalent interactions in tuning catalytic activity.
A plausible reaction mechanism has been proposed, contributing to the understanding of iron-catalyzed oxidation reactions.