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Published on: May 26, 2023
[A CASE OF PENILE PYODERMA GANGRENOSUM WITH STERILE ABSCESS SUCCESSFULLY TREATED WITH CORTICOSTEROIDS]
Tomoki Ohnishi1, Takuro Sunada1, Shingo Kitora1
1The Department of Urology, Kurashiki Central Hospital.
Hinyokika Kiyo. Acta Urologica Japonica
|June 30, 2026
Summary
Penile pyoderma gangrenosum, a rare inflammatory condition, can be diagnosed via biopsy. Steroid treatment effectively resolved symptoms and prevented recurrence in a 77-year-old male patient.
Area of Science:
- Urology
- Dermatology
- Pathology
Background:
- Pyoderma gangrenosum is a non-bacterial inflammatory condition causing ulcers and abscesses.
- Penile pyoderma gangrenosum can be worsened by surgical intervention for abscesses.
- Differential diagnosis for penile lesions includes cancer and infections.
Purpose of the Study:
- To report a case of penile pyoderma gangrenosum diagnosed minimally invasively.
- To highlight the efficacy of steroid therapy in managing penile pyoderma gangrenosum.
- To emphasize the importance of biopsy in differentiating penile conditions.
Main Methods:
- Clinical presentation and laboratory tests were used to rule out infection and malignancy.
- Magnetic resonance imaging identified fluid accumulation in the corpora cavernosa.
- Penile biopsy confirmed an abscess and ruled out malignancy.
Main Results:
- Biopsy revealed an abscess, not cancer.
- Steroid therapy led to rapid symptomatic improvement.
- The patient remained asymptomatic after 18 months of treatment and steroid discontinuation.
Conclusions:
- Minimally invasive diagnosis via biopsy is feasible for penile pyoderma gangrenosum.
- Steroid therapy is an effective treatment for penile pyoderma gangrenosum.
- Early diagnosis and appropriate treatment prevent recurrence and complications.
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