Related Experiment Video

Updated: Jul 2, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Clinically isolated aortitis: A diagnosis of exclusion?

Pradeep Vaideeswar1, Balaji Baste

  • 1Department of Pathology (Cardiovascular and Thoracic Division), Seth GS Medical College, Mumbai, Maharashtra, India.

Indian Journal of Pathology & Microbiology
|June 30, 2026
PubMed

Insights

Clinically isolated aortitis, an inflammation of the aorta, can occur with aneurysms or dissections. This condition is often an unexpected finding during surgery and lacks signs of other systemic diseases.

Area of Science:

  • Cardiovascular Pathology
  • Aortic Diseases

Background:

  • Ascending aortic aneurysms and dissections can lead to aortitis.
  • This aortitis is not linked to infection, vasculitis, or systemic diseases.
  • It is frequently discovered incidentally during surgical pathology.

Purpose of the Study:

  • To describe cases of clinically isolated aortitis.
  • To characterize the presentation and patient demographics.

Main Methods:

  • Retrospective case series analysis.
  • Review of surgical pathological findings.
  • Clinical data correlation.

Main Results:

  • Five cases of clinically isolated aortitis were identified.
  • Patients were in their fifth decade of life.
  • An almost equal sex distribution was observed.

Conclusions:

  • Clinically isolated aortitis is a distinct entity.
  • It presents as an incidental finding in aortic pathologies.
  • Further research may clarify its pathogenesis and clinical significance.
Keywords:
Aortitisclinically isolated aortitisinfectious aortitislarge-vessel vasculitisnon-infectious aortitis

More Related Videos

Isolation and Excision of Murine Aorta; A Versatile Technique in the Study of Cardiovascular Disease07:25

Isolation and Excision of Murine Aorta; A Versatile Technique in the Study of Cardiovascular Disease

Published on: November 24, 2014

Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...