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Gastroblastoma: Unveiling the mask of a rare entity
Lakshmi Rajagopal1, Neetu S Dathan1, Rachel Abraham1
1Department of Pathology, KIMSHEALTH, Trivandrum, Kerala, India.
Indian Journal of Pathology & Microbiology
|June 30, 2026
Abstract:
Gastroblastoma is a malignant epithelial tumor of the stomach, which is primarily diagnosed based on its biphasic histomorphology and the demonstration of its characteristic molecular fusion gene, MALAT1-GLI1. Variability in the histomorphology has not been studied so far owing to its rarity. With very few cases reported in the literature, its long-term course is not entirely understood, with most of the cases treated based on its stage.
