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Epistemological Issues in Clinical Reasoning: A Scoping Review
Gabriel Ferreira1, Marcus Vinícius Sehl Ferreira1, Gabriela Araújo1
1Unisinos University, São Leopoldo, Brazil.
Journal of Evaluation in Clinical Practice
|June 30, 2026
Summary
Clinical reasoning (CR) lacks a clear definition in medical literature, leading to errors. Clarifying CR
Area of Science:
- Medical Education
- Cognitive Science
- Philosophy of Medicine
Background:
- Clinical reasoning (CR) is crucial for accurate diagnoses and treatments.
- Significant uncertainty exists regarding the definition, scope, and methods of CR.
- Conceptual imprecision in CR contributes to medical errors and erodes patient trust.
Purpose of the Study:
- To map the definitions and conceptual frameworks of CR in medical and health sciences literature.
- To address the core issues of explainability and accountability in clinical reasoning.
- To synthesize diverse perspectives on CR to foster clarity and consensus.
Main Methods:
- A scoping review adhering to PRISMA-ScR guidelines was conducted.
- Systematic literature searches were performed across major databases (PubMed, Scopus, Web of Science, PhilPapers).
- Data were extracted and descriptively synthesized from 26 eligible studies by two independent reviewers.
Main Results:
- Five major conceptual perspectives on CR were identified: Integrative/Contextual, Dual-Process, Expertise/Tacit, Hypothetico-Deductive, and Outcome-Oriented.
- A significant number of studies (6/26) failed to provide explicit definitions of CR, highlighting its conceptual opacity.
- The literature reveals a lack of consensus, with diverse and sometimes conflicting views on CR.
Conclusions:
- The literature demonstrates substantial diversity and a critical lack of consensus on the definition of CR.
- CR requires conceptual clarity, explainability, and public justification, belonging to the "logical space of reasons".
- Making CR processes explicit is an epistemological and ethical imperative to reduce medical errors and improve medical education.
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