Related Experiment Video
Updated: Jul 2, 2026
Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
Published on: September 27, 2024
Absorbable Micro-Aesthetic Lifting Thread for Nasolabial Fold Correction: A Multicenter, Randomized,
Donghao Jia1, Kexin Song1, Wenyun Ting1
1Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Shuaifuyuan 1#, Dongcheng District, Beijing, 100730, People's Republic of China.
A novel absorbable micro-aesthetic lifting thread demonstrated non-inferiority for nasolabial fold correction compared to a marketed thread. It showed superior early aesthetic improvement and investigator satisfaction, with a comparable safety profile.
Area of Science:
- Aesthetic Medicine
- Biomaterials Science
- Dermatology
Background:
- Absorbable lifting threads are used for facial soft tissue support and NLF correction.
- These threads degrade naturally within the body post-implantation.
Purpose of the Study:
- To evaluate the efficacy and safety of a novel absorbable micro-aesthetic lifting thread.
- To compare this novel thread against a marketed polydioxanone thread for NLF correction.
Main Methods:
- A prospective, multicenter, randomized, evaluator-blinded, parallel-controlled study.
- 151 subjects with moderate-to-severe NLF (grade ≥3 WSRS) were randomized.
- Primary endpoint: 7-month WSRS response rate (≥1 grade improvement).
Main Results:
- The novel thread achieved a 7-month response rate of 71.6% vs. 62.7% for the control, confirming non-inferiority.
- The novel thread showed superiority in 3-month response rates, investigator satisfaction, and barb fixation (P<0.05).
- Both groups had comparable safety profiles with no serious adverse events.
Conclusions:
- The novel absorbable micro-aesthetic lifting thread is effective and safe for NLF correction.
- It demonstrates non-inferiority to a marketed comparator and offers potential advantages in early results and handling.
- The multi-plane lifting strategy combined with the novel thread shows promise for aesthetic outcomes.