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Related Concept Videos

Autism Spectrum Disorder01:19

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Modeling in Therapy01:26

Modeling in Therapy

Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in situations...

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Related Experiment Video

Updated: Jul 2, 2026

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
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Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting

Published on: June 6, 2020

Developing a consensus research definition for profound autism using a modified Delphi method.

Matthew Siegel1,2,3, Catherine L Lord4, Helen Tager-Flusberg5

  • 1Boston Children's Hospital, Boston, MA, USA.

Molecular Autism
|July 1, 2026
PubMed
Summary
This summary is machine-generated.

A new research definition for Profound Autism (PA) was developed to improve studies on this high-needs autistic population. This consensus-based definition will enhance research comparability and intervention targeting for individuals requiring lifelong care.

Keywords:
Autism spectrum disorderDelphi processProfound autism

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Last Updated: Jul 2, 2026

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Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Clinical Psychology

Background:

  • Autism spectrum disorder (ASD) diagnosis has evolved, with recent focus on high-functioning individuals.
  • Profound Autism (PA) is a proposed term for autistic individuals needing lifelong, 24/7 care.
  • Inconsistent research criteria for PA hinder understanding of strengths and needs.

Purpose of the Study:

  • To establish a consensus-based research definition for Profound Autism (PA).
  • To improve clarity and comparability in research on high-needs autistic individuals.
  • To facilitate targeted interventions and support for the PA population.

Main Methods:

  • A systematic, multi-stage Delphi consensus study.
  • Involved over 70 participants: researchers, caregivers, autistic individuals, and clinicians.
  • Utilized a series of questions across primary domains of interest.

Main Results:

  • 76% agreement on a research definition after two voting rounds.
  • Definition includes: age (≥8 years), ASD diagnosis, adaptive functioning below age level, need for supervision, and severely impaired cognition/limited verbal communication.
  • Criteria specify IQ < 50 and/or non-verbal communication limited to basic needs.

Conclusions:

  • A new working research definition for Profound Autism is proposed.
  • Adoption can enhance research comparability and generalizability of findings.
  • Aims to better target interventions and support for this high-needs group.