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Related Experiment Video

Updated: Jul 2, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
10:28

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Peri-Implant Tissue Stability Following Guided Bone Regeneration With Bioceramic: A Multicenter One-Year Cohort

Yulan Wang1,2, Jian Zhang3, Runfa Wu4

  • 1State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China.

Clinical Implant Dentistry and Related Research
|July 1, 2026
PubMed

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Summary

Guided bone regeneration (GBR) using bioceramic (BC) showed less buccal bone resorption around implants compared to xenograft (BO) one year after crown delivery. Bioceramic GBR offers stable bone outcomes for dental implants.

Area of Science:

  • Dental Implantology
  • Periodontology
  • Biomaterials Science

Background:

  • Guided bone regeneration (GBR) is crucial for dental implant success.
  • Comparing bioceramic (BC) and xenograft (BO) materials in GBR is essential for optimizing clinical outcomes.
  • Long-term stability of bone augmentation is a key concern in implant dentistry.

Purpose of the Study:

  • To compare the radiographic and clinical outcomes of GBR using bioceramic versus xenograft materials.
  • To evaluate buccal bone stability and implant survival rates one year after crown delivery.
  • To assess patient satisfaction following GBR procedures with different biomaterials.

Main Methods:

  • A multicenter prospective cohort study followed patients from a prior randomized controlled trial.
Keywords:
bioceramicsdental implantsguided bone regeneration (GBR)patient satisfactionperi‐implant health

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Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
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Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Published on: August 13, 2019

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Last Updated: Jul 2, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
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Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
08:41

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Published on: August 13, 2019

  • Buccal bone stability was assessed using CBCT, alongside implant survival, Probing Depth (PD), Bleeding on Probing (BOP), and Plaque Index (PI).
  • Patient satisfaction was measured using the Oral Health Impact Profile-5 (OHIP-5) questionnaire.

    • Main Results:

    • The implant survival rate was 100% in both bioceramic (BC) and xenograft (BO) groups.
    • Bioceramic (BC) group showed significantly less horizontal buccal bone thickness reduction (-0.28 mm) compared to the xenograft (BO) group (-0.91 mm) one year post-crown delivery (p=0.0000).
    • No significant differences were found in PI, BOP, or PD; patient satisfaction remained high in both groups.

    Conclusions:

    • Guided bone regeneration (GBR) with bioceramic material results in stable buccal bone on dental implants one year after crown placement.
    • Bioceramic appears to be a favorable material for GBR, minimizing bone resorption compared to xenografts.
    • Both materials support high implant survival rates and patient satisfaction, but bioceramic offers superior bone stability.