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Updated: Jul 3, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Clinicopathological Challenge: A Painful Violaceous Reticulated Patch
Seungmin Ko1, Dayeon Jung1, Yeji Jang1
1Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, Gyeonggi-do, Korea.
Hyaluronic acid injections for osteoarthritis can rarely cause vascular issues. This case highlights successful treatment of livedo racemosa with aspirin and topical fusidic acid, offering a conservative alternative.
Area of Science:
- Rheumatology
- Dermatology
- Vascular Medicine
Background:
- Hyaluronic acid (HA) injections are a common osteoarthritis treatment.
- Vascular complications from HA injections are rare, typically presenting as retiform purpura.
- Existing literature suggests heparin or hyaluronidase for management.
Purpose of the Study:
- To report a case of livedo racemosa following intra-articular (IA) HA injection.
- To describe a conservative treatment approach for this rare complication.
- To highlight the efficacy of acetylsalicylic acid monotherapy.
Main Methods:
- A patient developed livedo racemosa after IA HA injection.
- Treatment involved acetylsalicylic acid and topical fusidic acid.
- A conservative management strategy was employed.
Main Results:
- The livedo racemosa resolved successfully with the conservative treatment.
- Acetylsalicylic acid monotherapy proved effective.
- This contrasts with more aggressive treatments typically reported.
Conclusions:
- Vascular complications like livedo racemosa can occur after IA HA injections.
- Conservative management with acetylsalicylic acid may be a viable treatment option.
- Further research into antithrombotic strategies for HA complications is warranted.
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