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Related Concept Videos

Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

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Related Experiment Video

Updated: Jul 3, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Contemporary Concise Review 2025: Asthma.

Jun Miyata1, Koichi Fukunaga1

  • 1Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

Respirology (Carlton, Vic.)
|July 1, 2026
PubMed
Summary
This summary is machine-generated.

Asthma research in 2025 emphasizes anti-inflammatory relievers for mild cases and disease modification for severe asthma, including clinical remission. New insights into airway epithelium and microbiome advance understanding of asthma heterogeneity.

Keywords:
airway epitheliumasthmadisease modificationmicrobiomeoral corticosteroidremissiontreatable traits

Related Experiment Videos

Last Updated: Jul 3, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Area of Science:

  • Pulmonology and Respiratory Medicine
  • Translational Medicine
  • Precision Medicine

Background:

  • Asthma research in 2025 adopted a multidimensional approach, integrating disease trajectory, exacerbation risk, airway remodeling, comorbidities, and treatment response.
  • Mild asthma studies reinforced anti-inflammatory reliever strategies over short-acting beta-agonist (SABA)-only treatment, supporting inhaled corticosteroid use at symptom onset.

Purpose of the Study:

  • To explore advancements in asthma research, focusing on mild and severe asthma management, clinical remission, real-world implementation, and pathobiology.
  • To define clinical remission as a treatment target and research endpoint in severe asthma.
  • To highlight advances in understanding asthma heterogeneity through pathobiology.

Main Methods:

  • Review of studies published in 2025 on mild and severe asthma management.
  • Analysis of emerging consensus definitions, real-world data, and biologic trials for clinical remission.
  • Examination of pathobiology research focusing on airway epithelium, cellular ecosystems, microbiome, and early-life origins.

Main Results:

  • Mild asthma management increasingly favors anti-inflammatory relievers to reduce exacerbations.
  • Severe asthma research shifted towards disease modification, including oral corticosteroid sparing and clinical remission.
  • Real-world asthma care emphasized implementation strategies, biomarker use, digital health, and addressing health inequities.
  • Pathobiology research identified key factors like airway epithelium, microbiome, and early-life exposures in asthma heterogeneity.

Conclusions:

  • 2025 asthma research advanced a multidimensional understanding, promoting targeted therapies for mild and severe disease.
  • Clinical remission is emerging as a key target in severe asthma management.
  • Implementation science, digital health, and addressing inequities are crucial for real-world asthma care.
  • Advances in pathobiology provide deeper insights into the diverse mechanisms driving asthma heterogeneity.