Related Experiment Video
Updated: Jul 3, 2026

12:55
Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care
Published on: February 16, 2015
GPNMB-directed CAR-T cell therapies for solid tumors
Christopher W Mount1,2, Marcela V Maus3,4,5
1Krantz Family Center for Cancer Research, Massachusetts General Brigham Cancer Institute, Boston, MA, USA.
Nature Cancer
|July 1, 2026
Summary
No abstract available in PubMed .
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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
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