Dyke-Davidoff-Masson Syndrome: Neuroimaging Perspective of Infantile Versus Adult Presentation

Dyke-Davidoff-Masson syndrome (DDMS) is an uncommon clinicoradiological entity, characterized by cerebral hemiatrophy associated with compensatory calvarial and paranasal sinus changes following congenital or early acquired cerebral insult. We present comparative neuroimaging findings in infantile and adult presentations highlighting the temporal evolution of imaging features. This report presents the case of a 22-year-old male with refractory epilepsy who demonstrated classical features of DDMS with well-developed calvarial thickening and a 12-month-old infant showed marked cerebral hemiatrophy with minimal osseous remodeling. These findings emphasize the age-dependent imaging spectrum of DDMS. Thus, the importance of recognizing its evolving radiological features with age is critical.