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Updated: Jul 3, 2026

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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Real-Time Intravascular Ultrasound-Guided Percutaneous Coronary Intervention for Spontaneous Coronary Artery
Ahmed Elsherif1, Yi Lung Gan1, Ryan Khoo1
1Department of Interventional Cardiology, Queen Elizabeth Hospital, Birmingham, University Hospital Birmingham NHS Trust, Birmingham, United Kingdom.
JACC. Case Reports
|July 2, 2026
Summary
Spontaneous coronary artery dissection (SCAD) requires careful PCI. Intravascular ultrasound (IVUS) guided wiring in a side branch successfully advanced the guidewire into the true lumen, improving PCI safety.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Imaging
Background:
- Spontaneous coronary artery dissection (SCAD) is a cause of acute coronary syndrome (ACS), often affecting younger individuals without typical risk factors.
- Percutaneous coronary intervention (PCI) for SCAD has higher failure rates than for atherosclerotic coronary artery disease, mainly due to difficulties in wiring the true lumen.
- Intravascular ultrasound (IVUS) can enhance safety during SCAD PCI, but optimal guidewire techniques remain unclear.