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Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...

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Related Experiment Video

Updated: Jul 4, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

Quantitative Abdominal Aortic Calcification Morphology Is Associated With Lumen Geometry.

Gianna Elci, Zoraiz Bukhari, Pasani Dharmasena

    Journal of Vascular Research
    |July 2, 2026
    PubMed
    Summary
    This summary is machine-generated.

    Abdominal aortic calcification morphology, characterized by thickness and arc, is linked to reduced lumen area. These findings suggest calcification shape offers insights beyond just the total calcium amount.

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    Last Updated: Jul 4, 2026

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    Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

    Published on: January 15, 2022

    Area of Science:

    • Cardiovascular Imaging
    • Biomedical Engineering
    • Radiology

    Background:

    • Calcification morphology is well-studied in coronary arteries but poorly understood in the abdominal aorta.
    • It is unclear if calcification shape provides information beyond the total calcium burden.
    • Micro-computed tomography (micro-CT) offers near-histologic resolution for detailed analysis.

    Purpose of the Study:

    • To characterize abdominal aortic calcification morphology using micro-CT.
    • To evaluate the relationship between calcification morphology and local lumen geometry.

    Main Methods:

    • Abdominal aortic specimens from 19 cadavers were analyzed using micro-CT.
    • Calcification was classified as concentric or eccentric based on circumferential arc.
    • Measurements included calcium thickness, area, arc, and lumen area; statistical analysis used linear mixed-effects models.

    Main Results:

    • Lumen area did not differ significantly between concentric and eccentric calcifications.
    • Increased calcium thickness, area, and arc were each associated with smaller lumen area.
    • Sensitivity analyses confirmed significant associations for thickness and arc, but not area.

    Conclusions:

    • Quantitative morphologic features of abdominal aortic calcification are inversely associated with lumen area.
    • Calcification morphology provides structural information that complements the total calcium burden assessment.