Cognitive frailty in diabetic patients: A visual analysis based on CiteSpace

Area of Science:

• Endocrinology
• Gerontology
• Neuroscience

Background:

• Cognitive frailty, the combination of physical frailty and cognitive impairment, is increasingly recognized as a significant health concern.
• A strong association exists between diabetes mellitus and the development of cognitive frailty.
• Understanding the research landscape is crucial for advancing interventions and treatments.

Purpose of the Study:

• To conduct a bibliometric analysis of research on cognitive frailty and its relationship with diabetes.
• To identify key publications, influential authors, leading institutions, and emerging research trends.
• To map the intellectual structure and evolution of this research field.

Main Methods:

• Bibliometric analysis of literature published between 2005 and 2024.
• Data sourced from the Web of Science Core Collection.
• Bibliometric software CiteSpace utilized for analysis of publications, authors, institutions, and keywords.

Main Results:

• A total of 175 papers were identified, demonstrating a consistent increase in research output over time.
• King's College London emerged as a leading institution in the field.
• Pasquale Mone and Gaetano Santulli were identified as the most prolific authors.
• Key themes revealed include the interconnectedness of insulin resistance, chronic inflammation, and cognitive frailty.
• Recent research bursts indicate a focus on cognitive impairment and frailty as integrated clinical syndromes.

Conclusions:

• The study highlights the growing body of research on cognitive frailty in the context of diabetes.
• Insulin resistance and systemic inflammation are central pathological pathways.
• Future research is expected to focus on integrated clinical syndromes and their shared mechanisms.