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Updated: Jul 4, 2026
Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions
Published on: April 28, 2026
Submucosal tunneling endoscopic resection in challenging esophageal subepithelial lesions: a minimally invasive
Shaimaa Elkholy1, Hussein Okasha1, Abeer Awad1
1Gastroenterology Division, Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Background And Aims:
Submucosal tunneling endoscopic resection (STER) is a minimally invasive procedure for resecting esophageal subepithelial lesions (SELs), particularly those arising from the muscularis propria layer. This article presents 2 challenging cases of esophageal SELs successfully managed with STER.
Methods:
Two esophageal SELs were managed with STER, which involved creating a submucosal tunnel for en bloc resection, followed by closure with hemostatic clips. Challenges related to lesion location, size, and patient comorbidities were addressed during the procedures.
Results:
Both patients underwent successful en bloc resection of the SELs without adverse events. One presented with progressive dysphagia for 2 years, and the other with dysphagia and intermittent chest pain. Both experienced significant clinical improvement postoperatively.
Conclusions:
STER offers an effective, minimally invasive alternative to surgery in challenging cases of esophageal SELs, demonstrating excellent results with reduced morbidity when performed with careful planning and multidisciplinary collaboration.