Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pipe Flowrate Measurement: Problem Solving01:28

Pipe Flowrate Measurement: Problem Solving

A spray tank system is engineered to uniformly distribute a pest-control liquid across plants by using a pressurized mechanism. The tank, pressurized to 150 kPa, holds the pesticide at a height of 0.80 meters. Liquid flows from the tank through a 1.9 meter pipe with a diameter of 0.015 meters, angled at 0.698 radians, ultimately reaching a 0.007 meter nozzle that sprays the pesticide. Accurate calculation of the system's flow rate is crucial to ensure uniform application, and this is achieved...
Typical Model Studies01:30

Typical Model Studies

Fluid mechanics model studies often utilize scaled-down systems to predict fluid behavior in full-scale environments, such as river flows, dam spillways, and structures interacting with open surfaces. Maintaining Froude number similarity in river models is crucial, as it replicates surface flow features like wave patterns and velocities.
Steady, Laminar Flow Between Parallel Plates01:17

Steady, Laminar Flow Between Parallel Plates

Understanding steady, laminar flow between parallel plates is essential for analyzing and designing flow in narrow rectangular channels, commonly found in various water conveyance and drainage systems. The Navier-Stokes equations govern fluid motion and are generally challenging to solve due to their nonlinearity. However, simplifications are possible in certain cases, like the steady laminar flow between parallel plates. For this scenario, we assume steady, incompressible, laminar flow.
Capillarity in Fluid01:19

Capillarity in Fluid

Capillarity describes the movement of liquid in small spaces without external forces acting on it. The capillarity is driven by surface tension and adhesive interactions between the liquid and surrounding solid surfaces. This effect is often seen in narrow tubes, porous materials, and fine particles.
Surface tension is crucial to capillarity. It results from cohesive forces between liquid molecules at the liquid-air boundary, forming a skin that resists external forces. When the capillary tube...
Fluid Pressure over Flat Plate of Variable Width01:02

Fluid Pressure over Flat Plate of Variable Width

When a flat plate is submerged in a fluid, the fluid exerts pressure on the plate. This pressure can lead to many different phenomena, including drag and buoyancy. To understand the behavior of the fluid over a flat plate of variable width, it is essential to analyze the distribution of the pressure exerted.
The pressure distribution on the plate can be calculated by determining the force that acts on a differential area strip of the plate. Thus, the magnitude of the force is equal to the...
Steady, Laminar Flow in Circular Tubes01:23

Steady, Laminar Flow in Circular Tubes

Hagen-Poiseuille flow describes a viscous fluid's steady, incompressible flow through a cylindrical tube with a constant radius R. This flow profile is often applied to understand fluid transport in narrow channels, such as capillaries. It serves as a foundational example of laminar flow. In this model, cylindrical coordinates (r,θ,z) are used to describe the radial (r), angular (θ), and axial (z) dimensions within the tube. For Hagen-Poiseuille flow, the velocity profile is purely axial,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

To the homeRNAmax: Developing an Improved Blood Self-Collection and Stabilization Platform for Remote Transcriptomic Studies.

Analytical chemistry·2026
Same author

Reverse Transcriptase Activity with CRISPR (REACTR) Assay for Rapid and User-Friendly Therapeutic Drug Monitoring in Cytomegalovirus Care.

ACS infectious diseases·2026
Same author

Characterization of pre-analytical blood collection and stabilization parameters to maintain endogenous protein levels for remote blood sampling technology.

bioRxiv : the preprint server for biology·2026
Same author

From Fabrication to Flow: Impact of Print Orientation on Surface Qualities and Capillary-Driven Flow in Laser SLA-based Open Microchannels.

bioRxiv : the preprint server for biology·2026
Same author

Injury-induced paracrine effects on the podocyte's transcriptome.

American journal of physiology. Renal physiology·2026
Same author

Research In Your Mailbox: Remote Blood Self-sampling Enables Participation of Underserved Populations in Longitudinal Studies.

medRxiv : the preprint server for health sciences·2026

Related Experiment Video

Updated: Jul 4, 2026

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves
11:12

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves

Published on: October 17, 2013

Modeling and validation of parallel co-flows layer widths in open-capillary trigger valve systems.

T J Caira1, Jodie C Tokihiro1,2, Alya Shaposhnikov1

  • 1Department of Chemistry, University of Washington, Box 351700, Seattle, Washington 98195, United States.

Biorxiv : the Preprint Server for Biology
|July 3, 2026
PubMed
Summary

This study introduces a model for predicting fluid layer widths in open microfluidic systems using trigger valves. The research expands trigger valve applications in microfluidics for various biosensing and cell culture applications.

More Related Videos

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices
10:18

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

Published on: January 27, 2017

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section
11:00

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section

Published on: July 19, 2016

Related Experiment Videos

Last Updated: Jul 4, 2026

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves
11:12

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves

Published on: October 17, 2013

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices
10:18

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

Published on: January 27, 2017

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section
11:00

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section

Published on: July 19, 2016

Area of Science:

  • Microfluidics
  • Fluid Dynamics
  • Biotechnology

Background:

  • Fluid control is essential in microfluidic systems.
  • Trigger valves autonomously control fluid release using geometric features.
  • Previous work adapted closed trigger valve designs for open systems.

Purpose of the Study:

  • To present a model predicting parallel co-flow layer widths in open microfluidic devices.
  • To expand the use of trigger valves in open systems with varied configurations and materials.
  • To validate theoretical predictions with experimental data for fluid dynamics in open microfluidics.

Main Methods:

  • Developed a predictive model for layer widths based on side channel geometry.
  • Incorporated varied step heights and increased the number of trigger valves (up to seven).
  • Utilized diverse fluids and plastics in open microfluidic devices.
  • Established a theoretical framework for comparing predicted and experimental fluid dynamics.

Main Results:

  • Demonstrated layered co-flows with widths as low as 50 microns.
  • Successfully expanded trigger valve functionality in open microfluidic systems.
  • Validated theoretical predictions against experimental fluid travel distance, velocity, and layering width.

Conclusions:

  • The developed model accurately predicts fluid layer widths in open microfluidic systems.
  • Trigger valves are versatile for various applications, including hydrogel patterning, organ-on-a-chip models, and autonomous biosensing.
  • This work enhances the utility of open microfluidic devices for diverse scientific and diagnostic applications.