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Related Experiment Videos

Radiologically inserted gastrostomy in advanced amyotrophic lateral sclerosis: clinical outcomes.

María Varela-Cerdeira1, Laura Urraco Nieto2, Maria Antonia Gomez Mendieta3

  • 1Department of Palliative Care, Hospital Universitario La Paz, Madrid, Spain mvarelacerdeira@yahoo.com.

BMJ Supportive & Palliative Care
|July 3, 2026
PubMed
Summary

Related Concept Videos

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Enteral Nutrition I: Orogastric and Nasogastric Feeding01:26

Enteral Nutrition I: Orogastric and Nasogastric Feeding

Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...

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Amyotrophic lateral sclerosis & frontotemporal degeneration·2024

Radiologically inserted gastrostomy (RIG) in advanced amyotrophic lateral sclerosis (ALS) patients is safe and feasible, improving survival. Multidisciplinary care enhances outcomes and supports shared decision-making for patients with ALS.

Area of Science:

  • Neurology
  • Palliative Care

Background:

  • Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease impacting swallowing and nutrition.
  • Gastrostomy, including radiologically inserted gastrostomy (RIG), is a common intervention to support nutritional status in ALS.
  • Optimal timing and outcomes of gastrostomy in advanced ALS require further investigation.

Purpose of the Study:

  • To evaluate survival and clinical outcomes in amyotrophic lateral sclerosis (ALS) patients undergoing radiologically inserted gastrostomy (RIG).
  • To compare outcomes between ALS patients who received RIG and those for whom gastrostomy was indicated but not performed.

Main Methods:

  • Retrospective observational cohort study of 155 ALS patients (2018-2020) followed by a multidisciplinary palliative care team.
  • Patients classified as RIG or no RIG based on gastrostomy status.
Keywords:
Clinical assessmentDysphagiaNeurological conditionsPalliative CareSurvivorship

Related Experiment Videos

  • Survival analysis using Kaplan-Meier curves, stratified by baseline non-invasive ventilation (NIV) use.

    • Main Results:

    • Median survival after RIG was 14.7 months versus 8 months in non-RIG patients who died.
    • RIG was indicated in 53 patients, performed in 45; 65 patients did not undergo gastrostomy.
    • Baseline NIV use was associated with longer survival; no major safety concerns identified.

    Conclusions:

    • RIG is a safe and feasible intervention for advanced ALS patients.
    • Multidisciplinary care and palliative involvement optimize nutritional support and shared decision-making.
    • Further prospective studies are needed to confirm benefits and optimal timing for RIG intervention.