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Related Experiment Video

Updated: Jul 5, 2026

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments
05:19

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments

Published on: November 12, 2019

Active devices and systems for closed-loop neuromodulation.

Jingfei Wang1,2, Huize Xue1,2, Jiahao Li1,2,3

  • 1Institute of Optoelectronics & College of Future Information Technology, Shanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Fudan University, Shanghai, China.

Microsystems & Nanoengineering
|July 3, 2026
PubMed

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Summary
This summary is machine-generated.

Active devices offer advanced neuromodulation for precise neural regulation, integrating sensing and adaptive control. This review explores active devices for neuroscience and biomedical engineering applications.

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Neural Engineering

Background:

  • Neuromodulation is crucial for understanding and treating neurological disorders.
  • Current methods include electrical, optical, chemical, magnetic, and ultrasound stimulation.
  • Advances incorporate microsystems, nanotechnology, and optogenetics for enhanced neural control.

Purpose of the Study:

  • To review recent advances in active devices for neuromodulation.
  • To highlight the functional roles of active devices in neural regulation.
  • To provide insights into designing next-generation neural interfaces.

Main Methods:

  • Review of literature on active devices in neuromodulation.
  • Discussion of material platforms and device architectures.

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Last Updated: Jul 5, 2026

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments
05:19

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments

Published on: November 12, 2019

Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder
05:19

Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder

Published on: July 7, 2023

  • Emphasis on integrated sensing, amplification, and adaptive regulation.

    • Main Results:

    • Active devices enable precise spatial and temporal control over neural systems.
    • These devices are well-suited for system-level neuromodulation.
    • Recent innovations enhance the versatility and efficacy of neural regulation.

    Conclusions:

    • Active devices represent a significant advancement in neuromodulation.
    • Rational design of these devices is key for future neural interface systems.
    • Further research will drive therapeutic applications for neurological disorders.