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Cytomegalovirus enteritis in a patient with AKI after type B aortic dissection surgery: a case report

Tongkai Ge1, Junqiang Qiu2,3, Zhenzhong Wang2

  • 1Intensive Care Unit, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, P.R. China.

BMC Infectious Diseases
|July 4, 2026
PubMed
Abstract

Insights

Cytomegalovirus (CMV) enteritis can occur in patients with relative immunosuppression due to surgery and acute kidney injury (AKI). Early detection via CT imaging and prompt surgical intervention combined with antiviral therapy can be life-saving.

Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Surgical Oncology

Background:

  • Cytomegalovirus (CMV) enteritis is a rare condition associated with significant mortality and severe complications like gastrointestinal hemorrhage.
  • Patients without traditional immunocompromise can develop CMV enteritis under specific conditions.

Purpose of the Study:

  • To present the management of a CMV enteritis case in a patient with relative immunosuppression.
  • To highlight potential contributing factors and effective treatment strategies for CMV enteritis.

Main Methods:

  • Case report of a patient with a history of aortic surgery and acute kidney injury (AKI).
  • Diagnosis of CMV enteritis following massive gastrointestinal hemorrhage.
  • Treatment involved exploratory laparotomy, ganciclovir, and intravenous immunoglobulin.

Main Results:

  • Successful recovery following surgical intervention and antiviral therapy.
  • CT imaging proved valuable for detecting small bowel bleeding.
  • Post-surgical AKI and stress-induced immunosuppression identified as potential triggers.

Conclusions:

  • Relative immunosuppression post-surgery and AKI may predispose patients to CMV enteritis.
  • Prompt surgical intervention is crucial for life-threatening hemorrhage.
  • Antiviral therapy remains a primary treatment modality.
Keywords:
Acute kidney injuryCytomegalovirus enteritisObscure gastrointestinal bleedRelative immunosuppressionSurgical interventionType B aortic dissection

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