Periodontal Disease-Like Manifestations in Patients Having Acute Leukemia With Normal Complete Blood Counts

Acute leukemia (AL) is a malignant hematopoietic disease with a high fatality rate, and early detection and diagnosis are crucial for subsequent treatment. Clinically, oral manifestations, particularly the ones similar to those of periodontal disease, may be the first signs of AL. The present study reports two patients with complaints of gingival swelling and loosening of teeth, who had normal routine blood clinical tests. After bone marrow puncture, the patients were diagnosed with AL. Despite the blood tests being normal, abnormal gingival manifestations and unexplained looseness of teeth should be treated with suspicion, and AL should be considered a possible differential diagnosis.