Metachronous Bladder Metastases From Renal Cell Carcinoma: A Case Report

Renal cell carcinoma (RCC) is a common tumor of the urinary system, with several pathological subtypes, including clear cell, papillary, and chromophobe RCC. While RCC has the potential to metastasize to nearly any organ, metastasis to the urinary bladder is rare. We describe the case of a 76-year-old man who underwent right radical nephrectomy in July 2023. A follow-up CT scan was performed in October 2023, which showed no evidence of metastasis, but the patient was subsequently lost to follow-up. Twenty-five months later, he presented to the emergency department with hematuria. Imaging revealed a mass at the bladder neck and posteroinferior wall, along with additional metastatic lesions in the lungs, liver, and right adrenal gland. Transurethral resection was performed, and histopathology confirmed metastatic clear cell RCC. This case highlights the need to consider bladder metastasis in patients with a history of RCC who present with bladder lesions.