Related Experiment Video For paraganglioma
Updated: Jul 7, 2026
Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser
Published on: May 9, 2018
A Case of Bladder Paraganglioma With Negative Photodynamic Diagnosis Completely Resected by Staged En Bloc
Shu Gozu1, Yasukazu Nakanishi1, Gaku Okumura1
1Department of Urology National Cancer Center Hospital East Kashiwa-shi, Chiba Japan.
Introduction:
Bladder paraganglioma can be challenging to distinguish from nonpapillary bladder cancer. Here, we report a case of nonfunctional bladder paraganglioma treated with photodynamic diagnosis-assisted en bloc transurethral resection of the bladder tumor.
Case Presentation:
A 78-year-old man was incidentally diagnosed with a bladder tumor on imaging. Radiological and cystoscopic findings suggested bladder paraganglioma or nonpapillary urothelial carcinoma. The patient underwent en bloc transurethral resection of the bladder tumor with photodynamic diagnosis using 5-aminolevulinic acid. No fluorescence enhancement was observed during photodynamic diagnosis. Histopathological examination revealed nonfunctional bladder paraganglioma. A second-look en bloc transurethral resection with photodynamic diagnosis confirmed the absence of a residual tumor.
Conclusion:
This case highlights the diagnostic pitfalls of nonfunctional bladder paraganglioma presenting as a photodynamic diagnosis-negative bladder tumor and suggests that en bloc transurethral resection may be an effective organ-preserving approach in selected cases.
