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Updated: Jul 8, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Endovascular Therapy for Acute Ischemic Stroke: Current Evidence and Evolving Practices.
Brandon Doan1,2, Mohamad Abdalkader1, Farhan Khan3
1Departments of Radiology, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
Endovascular therapy (EVT) benefits patients with large-core infarcts and basilar artery occlusions. Recent evidence supports EVT for late-window stroke presentations, improving functional outcomes and reducing disability.
Area of Science:
- Neurology
- Interventional Radiology
- Stroke Medicine
Background:
- Endovascular therapy (EVT) has emerged as a critical treatment for acute ischemic stroke.
- Guidelines and evidence are evolving for specific patient populations and treatment windows.
Purpose of the Study:
- To review recent evidence and guidelines for EVT in challenging stroke scenarios.
- To assess EVT efficacy in large-core infarcts, basilar artery occlusions, and late-window presentations.
Main Methods:
- Literature review of recent studies and clinical guidelines.
- Analysis of functional outcomes and disability reduction associated with EVT.
Main Results:
- EVT demonstrates functional benefits in large-core infarcts and basilar artery occlusions compared to medical management.
- EVT reduces disability in late-window stroke patients selected via advanced imaging (CTA/CTP, MRI) or potentially NCCT.
- EVT is effective across various stroke severities and locations, including small and large infarcts.
Conclusions:
- EVT is a valuable treatment option for selected patients with large-core infarcts, basilar artery occlusions, and late-window strokes.
- Further research is needed to optimize EVT eligibility for very large infarcts, mild strokes, and medium vessel occlusions.
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