The semantic association Test of Quebec (TASQ): a novel measure of semantic associative processing with normative...

The Semantic Association Test of Quebec (TASQ) was developed as a clinically practical measure of semantic associative processing within semantic memory. This study aimed to establish normative data and provide preliminary evidence of clinical validity in Quebec French-speaking middle-aged and older adults. The TASQ comprises 64 semantic association items assessing abstract concepts, natural concepts, manmade concepts, and famous people. Following pilot testing, normative data were collected from 255 cognitively healthy French-speaking adults aged 50-92 years. Exploratory clinical validation was also conducted in healthy controls (n = 24), individuals with Mild Cognitive Impairment (n = 12), and individuals with Alzheimer's disease (n = 12). Pilot testing confirmed the feasibility and clarity of the task. TASQ total score performance was significantly associated with age and education. Regression-based normative correction was retained for the total score, whereas percentile distributions were generated for the total score and semantic subscales. Participants with Alzheimer's disease performed significantly more poorly than healthy controls across all TASQ measures. TASQ total score was strongly associated with global cognitive functioning. The TASQ appears to be a time-efficient and clinically practical measure of semantic processing, supported by normative data and preliminary evidence of clinical validity in aging and neurodegenerative disease.