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Updated: Jul 9, 2026

Clinical Anthropometrics and Body Composition from 3-Dimensional Optical Imaging
06:48

Clinical Anthropometrics and Body Composition from 3-Dimensional Optical Imaging

Published on: June 7, 2024

Reference method matters: DXA system differences influence agreement with 3D optical imaging body composition

Sophia Ramirez1, Miriam Bustami1, Christian Rodriguez1

  • 1Pennington Biomedical Research Center, LSU System, Baton Rouge, LA, USA.

International Journal of Obesity (2005)
|July 7, 2026
PubMed
Summary
This summary is machine-generated.

Conclusions about body composition accuracy vary based on the specific dual-energy X-ray absorptiometry (DXA) system used. Different DXA devices and software versions impact percent body fat (BF%) estimates from 3D optical imaging.

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Area of Science:

  • Biomedical Engineering
  • Anthropometry
  • Medical Imaging

Background:

  • Dual-energy X-ray absorptiometry (DXA) is the standard for validating body composition devices.
  • Previous studies highlight variations in DXA system component estimates.
  • This study investigates how different DXA systems affect conclusions about 3D optical (3DO) imaging accuracy.

Purpose of the Study:

  • To evaluate if percent body fat (BF%) estimates from 3D optical (3DO) imaging yield different conclusions when compared against various DXA systems and software versions.
  • To assess the agreement between 3DO BF% estimates and multiple DXA systems.

Main Methods:

  • Evaluated BF% in healthy adults using one 3DO imaging system and three DXA systems (Hologic Horizon A, Hologic Discovery A, GE Lunar iDXA).
  • All assessments were conducted on the same day.
  • Employed multiple statistical procedures, including linear correlations, Bland-Altman analyses, and mixed-effects models, to evaluate agreement.

Main Results:

  • Ninety-nine participants completed the study.
  • Agreement measures between 3DO and DXA systems varied, with Discovery A showing the best agreement relative to 3DO.
  • Significant differences in BF% estimates were found between 3DO and specific DXA systems (Horizon A, iDXA, Discovery A), with variations influenced by sex and BMI category.

Conclusions:

  • The choice of DXA device and software version significantly influences the perceived accuracy of other clinical body composition methods.
  • Conclusions drawn about a body composition method's accuracy are dependent on the reference DXA system used.
  • Differences in BF% estimates are not uniform across different populations (sex, BMI).