Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterizing the Epidemiology of Influenza A Viruses at the Swine-Human Interface: Study Protocol of the PigFluCam+ Project in Cambodia.

JMIR research protocols·2026
Same author

Age as a moderator of a brief alcohol intervention among injury patients in Northern Tanzania.

medRxiv : the preprint server for health sciences·2026
Same author

Disinvestment in Global Health Threatens Global Security and Children's Health Everywhere.

Journal of the Pediatric Infectious Diseases Society·2026
Same author

Trends and determinants of isoniazid preventive therapy initiation in antiretroviral therapy-treated HIV-positive adults in Tanzania Mainland 2015-2020: a retrospective observational study using medical records.

BMJ open·2026
Same author

Programmable antibody-based chimeric entry receptors for sarbecoviruses.

Communications biology·2026
Same author

NVX-CoV2372, monovalent mRNA and bivalent mRNA vaccines elicit broadly cross-reactive antibodies against emerging SARS-CoV-2 variants.

Human vaccines & immunotherapeutics·2026
Same journal

Characteristics and Risk Factors for Mortality of Vascular Graft Infections: a Cohort Study.

Open forum infectious diseases·2026
Same journal

Direct-Acting Antiviral Therapy and Long-Term Outcomes in Dialysis Patients With Hepatitis C: A Real-world Cohort Study.

Open forum infectious diseases·2026
Same journal

Three-Year CD4/CD8 Ratio Recovery After Initiation of Dual Versus Triple Integrase Inhibitor-Based Therapy in Naïve Adults With HIV.

Open forum infectious diseases·2026
Same journal

Long-Term Follow-Up of Patients With Classic Fever of Unknown Origin: Prognostic Outcomes and Management Strategies.

Open forum infectious diseases·2026
Same journal

Secondary Oral Vancomycin Prophylaxis and <i>Clostridioides difficile</i> Infection in Children and Young Adults With Cancer: A Retrospective Cohort Study.

Open forum infectious diseases·2026
Same journal

Impact of Multiplex PCR Blood-Culture Identification Panels on Clinical Outcomes, Antimicrobial Stewardship, and Economic Impact in US Hospitals: A Systematic Review and Meta-Analysis.

Open forum infectious diseases·2026
See all related articles

Related Experiment Video

Updated: Jul 9, 2026

High-throughput Detection of Respiratory Pathogens in Animal Specimens by Nanoscale PCR
11:00

High-throughput Detection of Respiratory Pathogens in Animal Specimens by Nanoscale PCR

Published on: November 28, 2016

Respiratory Pathogen Detection Among Febrile Inpatients in Northern Tanzania, 2016-2019.

Martin Linster1, Marina Zahari2, Yan Zhuang1

  • 1Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.

Open Forum Infectious Diseases
|July 8, 2026
PubMed
Summary
This summary is machine-generated.

Rhinovirus/enterovirus, influenza, and RSV were common in febrile inpatients in Tanzania, including those with severe acute respiratory infections. These findings are crucial for vaccine development in low-income countries.

Keywords:
Tanzaniafeverhospitalizationpathogenrespiratory infection

More Related Videos

Rapid Detection of Bacterial Pathogens Causing Lower Respiratory Tract Infections via Microfluidic-Chip-Based Loop-Mediated Isothermal Amplification
06:11

Rapid Detection of Bacterial Pathogens Causing Lower Respiratory Tract Infections via Microfluidic-Chip-Based Loop-Mediated Isothermal Amplification

Published on: March 29, 2024

Related Experiment Videos

Last Updated: Jul 9, 2026

High-throughput Detection of Respiratory Pathogens in Animal Specimens by Nanoscale PCR
11:00

High-throughput Detection of Respiratory Pathogens in Animal Specimens by Nanoscale PCR

Published on: November 28, 2016

Rapid Detection of Bacterial Pathogens Causing Lower Respiratory Tract Infections via Microfluidic-Chip-Based Loop-Mediated Isothermal Amplification
06:11

Rapid Detection of Bacterial Pathogens Causing Lower Respiratory Tract Infections via Microfluidic-Chip-Based Loop-Mediated Isothermal Amplification

Published on: March 29, 2024

Area of Science:

  • Infectious Diseases
  • Public Health
  • Virology

Background:

  • Febrile illness is a leading cause of hospitalization in sub-Saharan Africa, with unknown etiologies.
  • This study addresses knowledge gaps in respiratory pathogen identification in Tanzanian febrile inpatients.

Purpose of the Study:

  • To identify common respiratory pathogens in pediatric and adult inpatients with febrile illness in northern Tanzania.
  • To inform public health strategies and vaccine development for respiratory infections in low- and middle-income countries.

Main Methods:

  • A prospective cohort study enrolled 1132 febrile inpatients in two Tanzanian hospitals.
  • Nasopharyngeal/oropharyngeal specimens were tested for 19 respiratory pathogens using polymerase chain reaction (PCR).
  • Participants were stratified by age (<10 and ≥10 years) and illness severity (SARI, non-SARI respiratory, no respiratory illness).

Main Results:

  • Of 930 tested participants, 38.6% had at least one pathogen detected.
  • Rhinovirus/enterovirus (RV/EV), influenza, and adenovirus were most common in children (<10 years).
  • RV/EV and influenza were most common in older individuals (≥10 years), followed by RSV. Influenza, RV/EV, and RSV were prevalent in severe acute respiratory infection (SARI) cases.

Conclusions:

  • RV/EV, influenza, and RSV are significant pathogens in febrile inpatients, including SARI cases, in Tanzania.
  • These findings highlight the need for targeted interventions and vaccine strategies for respiratory infections in the region.
  • The results have implications for vaccine development and implementation in low- and middle-income countries.