Related Experiment Video
Updated: Jul 7, 2026

09:54
Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
Published on: December 3, 2019
Three-Year CD4/CD8 Ratio Recovery After Initiation of Dual Versus Triple Integrase Inhibitor-Based Therapy in Naïve
Roser Navarro-Soler1,2, Alejandro G García-Ruiz de Morales1,2, Juan Macías2,3
1Department of Infectious Diseases, Hospital Ramón y Cajal, IRYCIS, Madrid, Spain.
Open Forum Infectious Diseases
|July 6, 2026
Abstract:
From 21 233 adults in the Spanish HIV Research Network, we used propensity score matching to compare CD4/CD8 ratio recovery between dolutegravir-based 2DR and second-generation integrase inhibitor-based 3DR. No detectable differences in CD4/CD8 normalization were observed at 3 years across all cutoffs, suggesting that immune recovery does not differ between strategies.

