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Related Experiment Video

Updated: Jul 9, 2026

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
08:41

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Published on: August 13, 2019

Soft Tissue Augmentation Around Dental Implants - a Systematic Review.

Aishwarya Duble1, Hiroj Bagde2, Tapaswi Kamble1

  • 1Department of Periodontology and Implantology, Chhattisgarh Dental College and Research Institute, Sundra, Rajnandgaon, Chhattisgarh, India.

Maedica
|July 8, 2026
PubMed
Summary
This summary is machine-generated.

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Connective tissue grafts offer the most predictable results for long-term peri-implant soft tissue augmentation, enhancing width, thickness, and aesthetics. Substitute materials provide alternatives with less morbidity but more variable outcomes.

Area of Science:

  • Dental Implantology
  • Periodontology
  • Regenerative Medicine

Background:

  • Peri-implant soft tissue characteristics, including keratinized mucosa (KM) width and mucosal thickness (MT), are crucial for implant longevity and aesthetics.
  • Soft tissue augmentation (STA) techniques aim to improve these parameters, but their comparative long-term efficacy is not well-established.

Purpose of the Study:

  • To assess the medium- and long-term predictability of various peri-implant soft tissue augmentation techniques.
  • Evaluate outcomes related to peri-implant health, KM width, MT, marginal tissue stability, aesthetics, and patient-reported results.

Main Methods:

  • Systematic review and meta-analysis following PRISMA guidelines.
  • Included randomized controlled trials (RCTs) with ≥10 participants per arm and 6–60 months follow-up.
Keywords:
aestheticsconnective tissue graftdental implantskeratinized mucosamucosal thicknesssoft tissue augmentation

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Last Updated: Jul 9, 2026

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
08:41

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Published on: August 13, 2019

A Simplified Protocol for Protecting Palatal Soft Tissue Donor Sites Using an Oral Mucoadhesive Bandage
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  • Compared bilaminar or apically positioned flap techniques using autogenous grafts versus substitute materials (collagen matrix, acellular dermal matrix, volume-stable collagen matrix) or controls.
  • Main Results:

    • Twenty-seven RCTs met inclusion criteria; implant survival >95%.
    • Connective tissue grafts yielded superior gains in KM width, MT, tissue stability, and aesthetics, especially in anterior/aesthetic zones.
    • Autogenous grafts showed better marginal bone level preservation; volume-stable collagen matrix offered good stability with reduced donor morbidity.

    Conclusions:

    • Connective tissue grafts are the most predictable for long-term peri-implant soft tissue stability and aesthetics.
    • Substitute materials (acellular dermal matrix, collagen matrix, volume-stable collagen matrix) are viable alternatives when minimizing morbidity is key, though outcomes can be more variable.