A comprehensive portable electrochemical sensing system solution: a case study on malachite green detection
Liangxiu Jiang1,2, Fang Xie3, Liyang Duan4
1State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, China-Singapore Belt and Road Joint Laboratory on Infection Research and Drug Development, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China. zdyxyxkj@zju.edu.cn.
Abstract:
Developing portable electrochemical sensing platforms for on-site analysis remains a critical challenge for food safety and environmental monitoring due to the high cost and immobility of commercial instrumentation. In this study, we engineered a functionally integrated, miniaturized electrochemical circuit board that seamlessly supports both two- and three-electrode measurement systems. Validated through system simulations and experimental testing, the analytical capability of this custom platform successfully meets the requirements of portable electrochemical detection. As a proof-of-concept for food safety screening, we fabricated mesoporous silica-modified electrodes and integrated them with our portable system to quantitatively detect malachite green (MG) in fish sample extracts, displaying a response trend aligned with commercial systems. In addition, the successful implementation of alternative electrochemical methods further highlights the platform's exceptional potential for the point-of-care testing (POCT) of diverse environmental and biological targets.
