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Published on: July 4, 2018
Factors influencing the head and neck microbiome
Rasika Ekanayaka1, Akhilanand Chaurasia2
1Department of Oral Pathology, Faculty of Dental Sciences, University of Sri Jayewardenepura, Sri Lanka.
Advances in Immunology
|July 8, 2026
Summary
The head and neck microbiome maintains oral health. Imbalances, or dysbiosis, can lead to oral and systemic diseases due to complex host, environmental, and microbial interactions.
Area of Science:
- Microbiology
- Oral Biology
- Human Health
Background:
- The head and neck microbiome is a complex community of microorganisms essential for oral homeostasis.
- Dysbiosis, an imbalance in this microbiota, is linked to oral health issues and systemic diseases.
Purpose of the Study:
- To explore the intricate factors influencing the head and neck microbiome.
- To understand the interplay between host, environment, and microbial ecology in health and disease.
Main Methods:
- Review of existing literature on head and neck microbiome composition and function.
- Analysis of host-related factors (genetics, immunity, age), environmental influences, and microbial interactions.
Main Results:
- Microbial communities are shaped by host genetics, immune status, age, and physiological conditions.
- Anatomical sites and local environments create specific niches for distinct microbial populations.
- Microbial dynamics are influenced by diet, hygiene, systemic diseases, and immune dysregulation.
Conclusions:
- The head and neck microbiome plays a critical role in maintaining health.
- Alterations in the microbiome can result from a complex interplay of factors, impacting both oral and systemic health.
- Understanding these dynamics is crucial for addressing oral and related systemic conditions.
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