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Physical therapy protocols for patients with a megaprosthesis after bone tumor resection
Jorinde Jpm Denissen1, Niek Koenders1, Mart Ruks1
1Department of Rehabilitation, Radboud University Medical Center, Nijmegen, the Netherlands.
Disability and Rehabilitation
|July 8, 2026
Summary
This study developed practical physical therapy protocols for patients undergoing bone tumor resection and reconstruction with megaprostheses. These evidence-based guidelines aid physical therapists in optimizing patient recovery and function.
Area of Science:
- Orthopedic Oncology
- Rehabilitation Medicine
- Biomedical Engineering
Background:
- Bone tumors often require surgical resection and reconstruction with megaprostheses.
- Effective physical therapy is crucial for functional recovery in these patients.
- Standardized, evidence-based protocols are needed to guide physical therapists.
Purpose of the Study:
- To provide evidence-based guidance for physical therapists.
- To develop practical physical therapy protocols for patients treated with bone tumor resection and megaprostheses.
- To enhance post-operative care and functional outcomes.
Main Methods:
- Explorative literature search and consensus procedures involving orthopedic oncologic surgeons and physical therapists.
- Development and 1-year piloting of physical therapy protocols in patient care.
- Protocol refinement based on clinical experience and updated literature.
Main Results:
- Developed physical therapy protocols for six types of megaprostheses (hemipelvectomy, proximal femur, distal femur, total femur, proximal tibia, proximal humerus).
- Protocols are applicable to adult patients undergoing bone tumor resection and reconstruction.
- Protocols include specific goals, exercise therapy, and clinical considerations.
Conclusions:
- Practical, evidence-based physical therapy protocols have been established.
- These protocols offer essential guidance for physical therapists.
- The protocols aim to improve the management of patients undergoing bone tumor resection and megaprosthesis reconstruction.

