Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 10, 2026

Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles
08:26

Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles

Published on: October 19, 2015

Tutorial: strategies for targeting organelles using nanoparticles.

Na Feng1, Jialu Gao2, Leyi Wang1

  • 1Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Nature Protocols
|July 8, 2026
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy and related factors of levonorgestrel-releasing intrauterine system combined with metformin in fertility-preserving treatment for atypical endometrial hyperplasia and early endometrial cancer: A retrospective cohort study.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026
Same author

Osteoclast-Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025
Same author

Roles and potential mechanisms of hepatic stellate cells activation mediated by epigenetics through insulin like growth factor 1 and receptor: A review.

International journal of biological macromolecules·2025
Same author

Dynamic crosstalk between HSCs and liver microenvironment: multicellular interactions in the regulation of liver fibrosis.

Frontiers in cell and developmental biology·2025
Same author

Correction to "Deep Learning Enhanced Near Infrared-II Imaging and Image-Guided Small Interfering Ribonucleic Acid Therapy of Ischemic Stroke".

ACS nano·2025
Same author

Enhancing interfacial compatibility and performance of polylactic Acid/ poly(butylene adipate-co-terephthalate) blends via innovative reactive compatibilization.

International journal of biological macromolecules·2025
This summary is machine-generated.

Nanoparticles can be designed to target specific cell organelles for disease diagnosis and treatment. This guide details strategies for creating organelle-targeted nanomedicines for research and clinical applications.

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Nanotechnology

Background:

  • Organelle dysfunction is central to many diseases.
  • Targeting organelles offers precise diagnostic and therapeutic potential.
  • Nanotechnology provides tools for designing targeted nanoparticles.

Purpose of the Study:

  • To systematically review nanoparticle design strategies for organelle targeting.
  • To elucidate principles and methodologies for validating subcellular localization.
  • To guide the development of next-generation organelle-targeted nanomedicines.

Main Methods:

  • Review of nanoparticle design principles for organelle targeting.
  • Summary of experimental validation techniques for subcellular localization.

More Related Videos

3D Orbital Tracking in a Modified Two-photon Microscope: An Application to the Tracking of Intracellular Vesicles
11:28

3D Orbital Tracking in a Modified Two-photon Microscope: An Application to the Tracking of Intracellular Vesicles

Published on: October 1, 2014

Using In Vitro Live-cell Imaging to Explore Chemotherapeutics Delivered by Lipid-based Nanoparticles
10:26

Using In Vitro Live-cell Imaging to Explore Chemotherapeutics Delivered by Lipid-based Nanoparticles

Published on: November 1, 2017

Related Experiment Videos

Last Updated: Jul 10, 2026

Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles
08:26

Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles

Published on: October 19, 2015

3D Orbital Tracking in a Modified Two-photon Microscope: An Application to the Tracking of Intracellular Vesicles
11:28

3D Orbital Tracking in a Modified Two-photon Microscope: An Application to the Tracking of Intracellular Vesicles

Published on: October 1, 2014

Using In Vitro Live-cell Imaging to Explore Chemotherapeutics Delivered by Lipid-based Nanoparticles
10:26

Using In Vitro Live-cell Imaging to Explore Chemotherapeutics Delivered by Lipid-based Nanoparticles

Published on: November 1, 2017

  • Discussion of emerging trends in organelle-targeted nanomedicine.

    • Main Results:

    • Organelle-specific targeting strategies are summarized.
    • Fundamental principles of intracellular trafficking and localization are explained.
    • Methodologies for confirming nanoparticle localization within organelles are presented.

    Conclusions:

    • Nanoparticle design is crucial for effective organelle targeting.
    • This tutorial provides a framework for developing novel nanomedicines.
    • The field holds promise for both fundamental research and translational medicine.