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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

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Related Experiment Video

Updated: Jul 10, 2026

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
09:00

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients

Published on: April 13, 2021

Characterizing Middle Eastern and North African Patients in US Transplant Data.

Jesse Howell1, Jesse D Schold2, Lisa M McElroy3

  • 1Research Department, United Network for Organ Sharing, Richmond, VA.

Transplantation Direct
|July 9, 2026
PubMed
Summary

The study found differences in transplant waitlist metrics between Middle Eastern or North African (MENA) and non-MENA candidates. Separate reporting of MENA individuals may improve understanding of transplant equity.

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Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
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Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

Related Experiment Videos

Last Updated: Jul 10, 2026

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
09:00

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients

Published on: April 13, 2021

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

Area of Science:

  • Transplantation research
  • Health equity
  • Demographic analysis in healthcare

Background:

  • New US government guidelines mandate separate reporting for Middle Eastern or North African (MENA) populations.
  • Previous data did not distinguish MENA individuals, potentially obscuring disparities in organ transplantation.
  • This study addresses the need to understand pre-revision differences between MENA and non-MENA transplant candidates.

Purpose of the Study:

  • To compare demographic and clinical characteristics of Middle Eastern or North African (MENA) and non-MENA organ transplant candidates before the new reporting directive.
  • To identify potential disparities in waitlist times, medical urgency, and outcomes between these groups.
  • To inform future research and policy regarding equitable organ allocation.

Main Methods:

  • Analysis of Organ Procurement and Transplantation Network (OPTN) data for kidney, liver, heart, and lung transplants (2018-2023).
  • Inclusion of White, non-Hispanic US residents, categorizing Arab/Middle Eastern and North African individuals as MENA.
  • Comparison of demographics, survival rates, mortality, and time to transplant between MENA and non-MENA groups.

Main Results:

  • MENA candidates were younger, more often male, and more frequently listed for kidney transplants.
  • Significant differences observed in dialysis duration, medical urgency status, and median time to transplant between MENA and non-MENA candidates for specific organs.
  • One-year graft/patient survival rates were similar, but waitlist mortality and transplant rates varied by organ and ethnicity.

Conclusions:

  • Middle Eastern or North African (MENA) and non-MENA transplant candidates exhibit distinct characteristics and waitlist experiences.
  • Differences in dialysis time, medical urgency, and transplant timelines highlight the need for granular data.
  • Separate monitoring of MENA candidates post-revision is crucial for advancing transplant equity and understanding outcomes.