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Cost to implement an outpatient stewardship intervention for acute otitis media (AOM)

Leisha M Andersen1, Sophie E Katz2, Amy Keith3

  • 1American Academy of Pediatrics, USA.

Insights

Implementing interventions to reduce antibiotic duration for acute otitis media (AOM) in children incurs low costs. A high-intensity approach to antibiotic stewardship is more expensive than a low-intensity one.

Area of Science:

  • Health Services Research
  • Infectious Diseases
  • Pediatrics

Background:

  • National guidelines recommend 5-7 day antibiotic courses for acute otitis media (AOM) in children over 2 years.
  • Current practice often involves 10-day antibiotic prescriptions, potentially contributing to antibiotic resistance.
  • Implementation costs are frequently cited as a barrier to adopting shorter antibiotic durations.

Purpose of the Study:

  • To evaluate the implementation and sustainability costs of low-intensity and high-intensity interventions designed to reduce antibiotic duration for AOM.
  • To assess the cost-effectiveness of different intervention strategies in a clinical trial setting.

Main Methods:

  • A comparative cost analysis was conducted within a clinical trial involving 2 health systems and 46 clinics.
  • Implementation costs, including materials and personnel time, were recorded for each intervention.
  • Sustainability costs were estimated based on ongoing expenses.

Main Results:

  • Median implementation costs were $3,606 for the low-intensity intervention and $9,203 for the high-intensity intervention.
  • Personnel time was the primary cost driver (>90%) in both arms.
  • Sustainability costs were significantly lower for the low-intensity intervention ($133/year) compared to the high-intensity intervention ($764/year).

Conclusions:

  • Both low- and high-intensity interventions for reducing AOM antibiotic duration demonstrated low overall costs.
  • The high-intensity intervention incurred substantially higher implementation and sustainability costs than the low-intensity approach.
Abstract

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