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Cost to implement an outpatient stewardship intervention for acute otitis media (AOM)
Leisha M Andersen1, Sophie E Katz2, Amy Keith3
1American Academy of Pediatrics, USA.
Insights
Implementing interventions to reduce antibiotic duration for acute otitis media (AOM) in children incurs low costs. A high-intensity approach to antibiotic stewardship is more expensive than a low-intensity one.
Area of Science:
- Health Services Research
- Infectious Diseases
- Pediatrics
Background:
- National guidelines recommend 5-7 day antibiotic courses for acute otitis media (AOM) in children over 2 years.
- Current practice often involves 10-day antibiotic prescriptions, potentially contributing to antibiotic resistance.
- Implementation costs are frequently cited as a barrier to adopting shorter antibiotic durations.
Purpose of the Study:
- To evaluate the implementation and sustainability costs of low-intensity and high-intensity interventions designed to reduce antibiotic duration for AOM.
- To assess the cost-effectiveness of different intervention strategies in a clinical trial setting.
Main Methods:
- A comparative cost analysis was conducted within a clinical trial involving 2 health systems and 46 clinics.
- Implementation costs, including materials and personnel time, were recorded for each intervention.
- Sustainability costs were estimated based on ongoing expenses.
Main Results:
- Median implementation costs were $3,606 for the low-intensity intervention and $9,203 for the high-intensity intervention.
- Personnel time was the primary cost driver (>90%) in both arms.
- Sustainability costs were significantly lower for the low-intensity intervention ($133/year) compared to the high-intensity intervention ($764/year).
Conclusions:
- Both low- and high-intensity interventions for reducing AOM antibiotic duration demonstrated low overall costs.
- The high-intensity intervention incurred substantially higher implementation and sustainability costs than the low-intensity approach.
Objective:
Most children 2 years and older with uncomplicated acute otitis media (AOM) are prescribed 10-day antibiotic durations, despite national guidelines recommending antibiotics for 5-7 days. Costs are often cited as a barrier to stewardship efforts. As part of a larger clinical trial including 2 systems and 46 clinics, we developed a low-intensity and a high-intensity intervention aimed at reducing antibiotic duration for AOM and evaluated implementation and sustainability for the interventions.
Methods:
Costs associated with each implementation activity were recorded over time, including material/supply costs (eg, printing) and personnel time costs. Sustainability costs were estimated based on ongoing implementation expenses. For each system, we assessed total intervention, activity-specific, and sustainability costs. Aggregate results were reported as the median across systems.
Results:
The total median implementation costs were $3,606 (range $2,540-$4,672) for the low-intensity intervention and $9,203 (range $7,557-$10,849) for the high-intensity intervention. For the low-intensity intervention, the primary cost driver was electronic health record modifications totaling $2,292 (range $1,615-$2,968). For the high-intensity intervention, the primary cost driver was audit and feedback system activation totaling $5,597 (range $2,885-$8,309). Personnel time accounted for over 90% of costs in both study arms. Sustainability costs were $133/year (range $77-$190) for the low-intensity intervention and $764/year (range $628-$901) for the high-intensity intervention.
Conclusions:
Overall costs were low. The high-intensity intervention resulted in higher costs compared to the low-intensity intervention.
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