A step-by-step guide for isolating soluble and insoluble chromatin followed by next-generation sequencing library

Shan Hua1, Miraz A Sadi2, Brandon J Park3

  • 1Cornell University, Department of Molecular Biology and Genetics, Ithaca, NY, USA; University of Rochester Medical Center, Department of Biomedical Genetics, Rochester, NY, USA.

STAR Protocols
|July 9, 2026
PubMed