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Related Concept Videos

Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...

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Updated: Jun 23, 2026

A Periprosthetic Joint Candida albicans Infection Model in Mouse
04:37

A Periprosthetic Joint Candida albicans Infection Model in Mouse

Published on: February 2, 2024

Proliferative Periostitis: Often Overlooked Onion-Skinning.

Reed A McKinney1, Caitlyn A Menicucci2, Logan C Helquist3

  • 1Department of Pathology, Brooke Army Medical Center, Joint Base San Antonio, Fort Sam Houston, San Antonio, TX, 78234, USA. reedamckin@gmail.com.

Head and Neck Pathology
|June 20, 2026
PubMed
Summary
This summary is machine-generated.

Proliferative periostitis, a rare bone growth, often affects children due to chronic inflammation. Recognizing its key features in imaging and tissue samples is crucial for accurate diagnosis.

Keywords:
Garré osteomyelitisMandiblePediatricProliferative periostitis

Related Experiment Videos

Last Updated: Jun 23, 2026

A Periprosthetic Joint Candida albicans Infection Model in Mouse
04:37

A Periprosthetic Joint Candida albicans Infection Model in Mouse

Published on: February 2, 2024

Area of Science:

  • Oral and Maxillofacial Radiology
  • Pediatric Dentistry
  • Pathology

Background:

  • Proliferative periostitis, or Garré osteomyelitis, is an uncommon periosteal reaction.
  • Characterized by reactive bone formation due to chronic low-grade inflammation or infection.
  • Most frequently observed in pediatric patients.

Purpose of the Study:

  • To describe a case of proliferative periostitis in a pediatric patient.
  • To correlate clinical, radiographic, and histologic findings for diagnosis.

Main Methods:

  • Case report of a 6-year-old female with cheek swelling.
  • Clinical examination of swelling along the buccal aspect of tooth #30 and lateral mandible.
  • Radiographic and histologic evaluation of the affected area.

Main Results:

  • The patient presented with a two-week history of right cheek swelling.
  • Clinical, radiographic, and histologic findings were consistent with proliferative periostitis.
  • The diagnosis was confirmed through comprehensive evaluation.

Conclusions:

  • Familiarity with the radiographic and histologic findings of proliferative periostitis is essential.
  • Accurate diagnosis relies on integrating clinical, radiographic, and histologic data.
  • Early recognition aids in appropriate management of this condition.