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Development of Multiplex Real-Time RT-qPCR Assays for the Detection of SARS-CoV-2, Influenza A/B, and MERS-CoV
Published on: November 10, 2023
Viral co-infection with SARS-CoV-2 in hospitalized Peruvian patients during 2020-2021
Carlos Augusto Yabar1,2, Karolyn Vega-Chozo3, Eduardo Miranda-Ulloa4
1Innovation and Diagnostic Support Unit, National Institute of Health, Lima, Peru.
Abstract:
The study aimed to identify coinfections of SARS-CoV-2 with other viruses in patients with moderate and severe COVID-19. 98 patients from Lima, San Martín, and Loreto were selected, from whom nasopharyngeal secretion, blood, and urine samples were taken and analyzed using serological and molecular tests to detect HTLV, HIV, hepatitis B, dengue, Chikungunya, Zika, and a panel of respiratory viruses (influenza A/B, rhinovirus, respiratory syncytial virus, metapneumovirus, and adenovirus). The results showed two cases of coinfection (2/98; 2%): one with SARS-CoV-2/rhinovirus and another with SARS-CoV-2/HTLV-2. Both patients presented with COVID-19-associated pneumonia but progressed favorably. It is concluded that the frequency of viral coinfection in patients from health facilities in the Peruvian coast and jungle with moderate and severe cases of COVID-19 was low.
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