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Updated: Jul 12, 2026

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors
Published on: September 27, 2019
Adjunctive Management of Itch in Atopic Dermatitis.
Sarah G Brooks1, Gil Yosipovitch1
1Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, Miami Itch Center, University of Miami Miller School of Medicine, 5555 Ponce de Leon Boulevard, Coral Gables, FL 33146, USA.
Managing itch in atopic dermatitis (AD) is crucial. This review covers new topical and systemic adjunctive therapies for AD, focusing on their safety and effectiveness in reducing itch.
Area of Science:
- Dermatology
- Immunology
- Pharmacology
Background:
- Atopic dermatitis (AD) is a chronic inflammatory skin condition with complex causes and varied symptoms.
- Itch is a primary symptom of AD, significantly impairing patients' quality of life.
- Effective itch management is essential for reducing the overall burden of AD.
Purpose of the Study:
- To review the latest clinical trial data on adjunctive therapies for atopic dermatitis.
- To evaluate the safety and efficacy of emerging topical and systemic treatments for AD itch.
- To provide an overview of current supplemental treatment options for AD management.
Main Methods:
- Literature review of recent clinical trials and studies.
- Analysis of safety and efficacy data for topical and systemic adjunctive therapies.
- Synthesis of current evidence on novel treatments for atopic dermatitis itch.
Main Results:
- Emerging topical and systemic therapies show promise in reducing AD-associated itch.
- Data on the safety profiles of these adjunctive treatments are being collected.
- Efficacy varies among different therapeutic options, requiring individualized treatment approaches.
Conclusions:
- Adjunctive therapies offer new avenues for managing itch in atopic dermatitis.
- Continued research is vital to establish the long-term safety and effectiveness of these treatments.
- Optimizing itch control is key to improving the quality of life for individuals with AD.
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