Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Bioremediation of Plastics01:28

Microbial Bioremediation of Plastics

Polyethylene terephthalate (PET) is a synthetic polymer widely utilized in the packaging industry, particularly for bottles and containers. Due to its chemical stability and durability, PET accumulates in the environment, contributing significantly to plastic pollution. It comprises repeating units of terephthalic acid and ethylene glycol, resulting in a semi-crystalline structure that is resistant to natural degradation processes.A notable breakthrough in plastic biodegradation came with the...
Bioplastics01:27

Bioplastics

Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Parsing the Drivers of Bronchiolar Mucus Plugs in Severe Asthma.

American journal of respiratory and critical care medicine·2026
Same author

Sex matters: IgE-associated nasal epithelial gene expression in asthma.

The Journal of allergy and clinical immunology·2026
Same author

Breathomics in Diabetes Management: A Noninvasive Approach for Precision Health Monitoring.

Journal of diabetes research·2026
Same author

Association of proteins involved in fetal lung development with respiratory outcomes in infancy.

Respiratory medicine·2026
Same author

Four-year Experience of Videoconferencing-based Telepsychiatry Service in Patan Hospital: An Observational Study.

JNMA; journal of the Nepal Medical Association·2026
Same author

Mechanistic Insights into PFAS Adsorption on Microplastics: Effects of Contaminant Properties and Water Chemistry.

Environmental research·2026

Related Experiment Video

Updated: Jul 12, 2026

Multimodal Analysis of Microplastics in Drinking Water using a Silicon Nanomembrane Analysis Pipeline
09:10

Multimodal Analysis of Microplastics in Drinking Water using a Silicon Nanomembrane Analysis Pipeline

Published on: June 13, 2025

Emerging Analytical Methodologies for Micro- and Nano-Plastics Detection in Human Samples: Analytical Challenges and

Jyoti Varma1, Jeganathan Chinnadurai2, Pei-Chien Tsai1,3

  • 1Department of Medicinal and Applied Chemistry, College of Life Science, Kaohsiung Medical University, Kaohsiung City, Taiwan.

Critical Reviews in Analytical Chemistry
|July 10, 2026
PubMed
Summary

Micro- and nanoplastics (MNPs) are found in human samples, but analytical challenges hinder accurate detection and risk assessment. Standardized methods are needed for reliable biomonitoring and health impact evaluation.

Keywords:
Analytical methodologiesPy-GC-MSbiomonitoringcontamination controlhealth effectshuman systemmicro- and nanoplastics (MNPs)toxicologyµ-FTIRµ-Raman

More Related Videos

Extraction of Organochlorine Pesticides from Plastic Pellets and Plastic Type Analysis
10:12

Extraction of Organochlorine Pesticides from Plastic Pellets and Plastic Type Analysis

Published on: July 1, 2017

Quantification of Polybutylene Adipate Terephthalate-based Micro- and Nano-plastics from Soil Using Proton Nuclear Magnetic Resonance Spectroscopy
05:05

Quantification of Polybutylene Adipate Terephthalate-based Micro- and Nano-plastics from Soil Using Proton Nuclear Magnetic Resonance Spectroscopy

Published on: June 6, 2025

Related Experiment Videos

Last Updated: Jul 12, 2026

Multimodal Analysis of Microplastics in Drinking Water using a Silicon Nanomembrane Analysis Pipeline
09:10

Multimodal Analysis of Microplastics in Drinking Water using a Silicon Nanomembrane Analysis Pipeline

Published on: June 13, 2025

Extraction of Organochlorine Pesticides from Plastic Pellets and Plastic Type Analysis
10:12

Extraction of Organochlorine Pesticides from Plastic Pellets and Plastic Type Analysis

Published on: July 1, 2017

Quantification of Polybutylene Adipate Terephthalate-based Micro- and Nano-plastics from Soil Using Proton Nuclear Magnetic Resonance Spectroscopy
05:05

Quantification of Polybutylene Adipate Terephthalate-based Micro- and Nano-plastics from Soil Using Proton Nuclear Magnetic Resonance Spectroscopy

Published on: June 6, 2025

Area of Science:

  • Environmental Science
  • Toxicology
  • Analytical Chemistry

Background:

  • Micro- and nanoplastics (MNPs) are increasingly detected in human tissues and biofluids.
  • Growing evidence of human exposure raises concerns about potential health impacts.

Purpose of the Study:

  • Critically evaluate sample preparation, detection methodologies, and toxicological evidence for MNPs in human biological samples.
  • Identify analytical challenges and limitations in current MNP characterization.

Main Methods:

  • Review of sample preparation strategies (e.g., digestion methods).
  • Assessment of detection methodologies (e.g., microscopy, spectroscopy, pyrolysis-GC-MS).
  • Evaluation of toxicological data and epidemiological evidence.

Main Results:

  • Sample preparation significantly impacts MNP accuracy and comparability; harsh methods risk polymer degradation, while mild methods leave residues.
  • No single analytical technique can accurately provide sizing, polymer identification, and mass quantification simultaneously.
  • Nanoplastics are severely under-quantified due to detection limits, hindering assessment of the most biologically relevant fraction.
  • Experimental evidence suggests MNPs <10 µm can induce cellular stress, but human disease links remain correlational.

Conclusions:

  • Standardized protocols, certified reference materials, and validated nanoplastic detection methods are urgently required.
  • Integrated multi-analytical strategies are needed for reliable MNP biomonitoring and exposure-risk assessment.
  • Addressing analytical limitations is crucial for understanding MNP health impacts.