Related Experiment Videos
Poor adherence to cancer therapy in Ethiopia: systematic review and meta-analysis
Astewle Andargie Baye1, Yirgalem Abere1, Demewoz Kefale1
1Department of Adult Health Nursing, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.
Objectives:
Poor adherence significantly compromises the effectiveness and success of cancer treatment. Understanding the full scope and contributing factors of poor adherence is essential for improving patient care. Therefore, this review aimed to determine the pooled prevalence of poor adherence to cancer therapy in Ethiopia.
Methods:
The preliminary concepts were registered into PROSPERO. Comprehensive searches of multiple databases were conducted to identify relevant articles. A random-effects model was used to estimate the pooled effect size. Heterogeneity was assessed using the I2 statistic. Publication bias was evaluated through both qualitative and quantitative methods. Additionally, a sensitivity analysis was done to ensure the robustness of the studies.
Results:
The analysis includes 15 studies with a total of 7,115 cancer patients. The result indicates that, the overall pooled prevalence of poor adherence to cancer therapy in Ethiopia was 41.45% (95% CI: 33.37-49.52). Comorbidity, treatment side-effects, and residency settings are factors independently associated with poor adherence.
Conclusion:
Poor adherence to cancer therapy in Ethiopia is significant. Therefore, efforts are needed to increase adherence. Comprehensive and timely management of comorbid conditions and treatment adverse effects can increase adherence to treatment.
Related Concept Videos
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Targeted Cancer Therapies
There are several types of targeted therapies against specific...
Therapeutic Drug Monitoring: Affecting Factors
Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's cancer...
Treatment Resistant Cancers
Treatment Resistent Cancers