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Tantalum-Based Nanomaterials: From Properties to Biomedical Applications
Yutong Jin1,2, Yupeng Zhang1,2, Chen Yang2
1School of Pharmacy, China Medical University, Shenyang, China.
Advanced Materials (Deerfield Beach, Fla.)
|July 10, 2026
Summary
Tantalum-based nanomaterials (TBNs) show great promise for diverse biomedical uses, from biosensing to cancer therapy. This review integrates TBN research, highlighting applications and future clinical translation potential.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Medical Devices
Background:
- Tantalum is a well-established surgical implant material due to its stability and biocompatibility.
- Nanotechnology has enabled the development of tantalum-based nanomaterials (TBNs) with tunable properties.
- Existing reviews lack a comprehensive integration of diverse TBNs and their biomedical applications.
Purpose of the Study:
- To systematically review the latest research on TBNs.
- To highlight the performance advantages and diverse biomedical applications of TBNs.
- To identify challenges and future prospects for TBNs in clinical translation.
Main Methods:
- Systematic literature review of TBN research.
- Analysis of TBN properties and performance.
- Categorization of TBN applications in biosensing, medical imaging, tissue engineering, anti-tumor therapy, embolization, and radiation protection.
Main Results:
- TBNs offer adjustable physicochemical and biological properties for advanced biomedical applications.
- Significant applications include biosensing, medical imaging, tissue engineering, anti-tumor therapy, embolization, and radiation protection.
- The review provides a consolidated overview of TBNs' potential.
Conclusions:
- TBNs are highly promising for a wide range of biomedical applications.
- Further research is needed to address current challenges and promote clinical translation.
- TBNs hold potential for developing integrated diagnosis and treatment platforms.

