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Updated: Jul 12, 2026
09:16
A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
Published on: January 22, 2016
Medical Symptoms and Psychiatric Comorbidities in People with Methamphetamine Use Disorder
Rodrigo Marín-Navarrete1, Ricardo Sánchez-Domínguez2, Carmen Fernández-Cáceres3
1Dirección de Investigación y Enseñanza, Centros de Integración Juvenil A.C, Ciudad de México, México.
Journal of Dual Diagnosis
|July 10, 2026
Summary
Long-term methamphetamine use causes significant physical and mental health issues, including anxiety, depression, psychosis, and cardiac problems. Effective treatment requires comprehensive, multidisciplinary care to manage these complex complications.
Area of Science:
- Addiction Medicine
- Psychiatry
- Public Health
Background:
- Long-term methamphetamine use is linked to severe physical health issues like chest pain, cardiac complications, hypertension, and gastric problems.
- Mental health consequences include hallucinations, anxiety, depression, psychosis, and paranoia.
Purpose of the Study:
- To characterize and identify the medical symptoms and psychiatric comorbidities in individuals with methamphetamine use disorder (MUD).
Main Methods:
- A secondary database analysis was conducted using medical records from 2014 to 2021.
- A sample of 8,713 patients diagnosed with MUD was analyzed from a larger cohort of 208,764 patients.
Main Results:
- High prevalence of co-occurring substance use, including tobacco (85.8%), alcohol (68.1%), and marijuana (31.2%).
- Most common psychiatric comorbidities were anxiety (25.2%), depressive (23.9%), and psychotic (11.3%) disorders.
- Frequently reported medical conditions included tachycardia (10.1%), gastritis (9.8%), depression (16.7%), anxiety (13.3%), insomnia (12.1%), psychosis (13.6%), myalgia (7.8%), and dyspnea (6.4%).
Conclusions:
- Methamphetamine use disorder is associated with a wide spectrum of medical and psychiatric conditions.
- Addressing the complications of methamphetamine use necessitates multidisciplinary care approaches.
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