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Point-of-care testing (POCT) for Infectious diseases: technological innovation, effectiveness evaluation, and
1Mianyang Hospital of Traditional Chinese Medicine, Mianyang 621000, Sichuan Province, PR China.
Point-of-care testing (POCT) enhances infectious disease diagnosis through rapid molecular diagnostics, biosensing, and AI. This review covers quality assessment and strategies for resource-limited settings, guiding future POCT development.
Area of Science:
- In vitro diagnostics
- Public health
- Biotechnology
Background:
- Point-of-care testing (POCT) is vital for rapid infectious disease screening, surveillance, and prevention.
- POCT offers convenience and efficiency, crucial for timely public health interventions.
Purpose of the Study:
- To systematically review innovative POCT technologies for infectious diseases.
- To analyze quality assessment systems and application strategies for POCT.
- To propose future development directions for POCT in infectious disease management.
Main Methods:
- Systematic review of recent advancements in POCT technologies.
- Analysis of quality assessment indicators (sensitivity, specificity, detection limit, stability, field applicability).
- Evaluation of application strategies in resource-limited settings.
Main Results:
- Recent innovations include molecular diagnostics, microfluidic systems, biosensing, and AI in POCT.
- Quality assessment is crucial, focusing on key performance indicators.
- Strategies for resource-limited settings involve optimizing technical applicability and resource allocation.
Conclusions:
- POCT technologies are rapidly evolving for infectious diseases.
- Effective quality assessment and tailored strategies are essential for widespread POCT implementation.
- Future directions aim to address current challenges and enhance POCT utility globally.
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