Simulation-guided biomimetic sharp-edged ultrasonic microreactor enables morphology-uniform and performance-tunable...

Halide perovskite quantum dots (HPQDs) are transformative candidates for next-generation optoelectronic devices, owing to their exceptional optoelectronic properties including widely tunable bandgaps, ultrahigh color purity, and solution processability. However, scalable, deterministic synthesis of high-quality HPQDs with simultaneous ultra-narrow emission linewidth and high photoluminescence quantum yield (PLQY) remains a longstanding challenge, fundamentally limited by the mass transfer bottleneck and poor mixing efficiency of conventional laminar microreactors. Here, we report a biomimetic vein-inspired ultrasonic microreactor integrated with sharp-edged microstructure arrays to address this core challenge. Through systematic multiphysics simulations, we quantitatively decode the acoustic-hydrodynamic coupling mechanism in the microreactor, and establish a quantitative structure-performance relationship between microstructure geometry and sonochemical reaction performance. We identify an optimized cylindrical microstructure configuration that synergistically amplifies acoustic streaming and cavitation yield to break laminar boundary layer confinement. Experimental validation confirms the optimized microreactor enables continuous synthesis of high-quality HPQDs with an ultra-narrow full width at half maximum of 23.28 nm and PLQY up to 78.6%, markedly outperforming conventional microfluidic methods. We further elucidate that cavitation-enhanced micromixing enables dynamic supersaturation tuning, driving LaMer-type size-focusing and homogeneous nucleation for exceptional HPQDs monodispersity. This work provides a generalizable, scalable microfluidic strategy for precision synthesis of high-performance optoelectronic nanomaterials, bridging the critical gap between lab-scale research and industrial translation.