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A third way to breathe
1Department of Genome Biology, Graduate School of Medicine, The University of Osaka, Suita, Osaka, Japan; Human Biology Research Unit, Institute of Integrated Research, Institute of Science Tokyo (Science Tokyo), Bunkyo, Tokyo, Japan; Premium Research Institute for Human Metaverse Medicine (WPI-PRIMe), The University of Osaka, Suita, Osaka, Japan; Division of Gastroenterology, Hepatology and Nutrition, Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Center for Stem Cell and Organoid Medicine (CuSTOM), Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Communication Design Center, Advanced Medical Research Center, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa 236-0004, Japan.
Abstract:
In this Backstory, the authors recount how a question inspired by loach intestinal breathing grew into enteral ventilation with oxygenated perfluorodecalin: a translational effort shaped by multidisciplinary collaboration, large-animal validation, and the urgency of helping patients whose lungs can no longer cope.
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