Performance of compressed-sensing cardiac accelerated cine MR in evaluating left ventricular function: a systematic...

Area of Science:

• Cardiovascular Imaging
• Medical Physics
• Radiology

Background:

• Cardiac magnetic resonance (CMR) imaging is crucial for assessing left ventricular (LV) characteristics.
• Compressed-sensing (CS) accelerated cine sequences offer faster image acquisition compared to standard segmented cine (Std-cine) sequences.
• Assessing the consistency of LV parameters between CS-cine and Std-cine is essential for clinical adoption.

Purpose of the Study:

• To evaluate the consistency of LV characteristics derived from CS-accelerated cine CMR images compared to Std-cine sequences.
• To compare image quality between CS-cine and Std-cine acquisitions.
• To investigate potential differences in consistency across various subgroups, including pediatric populations and patients with arrhythmias.

Main Methods:

• A systematic review and meta-analysis of studies comparing CS-cine and Std-cine sequences within the same participants.
• Data extraction focused on LV ejection fraction (LVEF), volume, mass, and image quality.
• Subgroup analyses were performed based on age (children), breath-hold status, presence of arrhythmias, and MRI field strength.

Main Results:

• Thirty-five studies were included in the meta-analysis.
• No significant differences were found in LVEF, LV volume, or LV mass between CS-cine and Std-cine (all p > 0.05).
• Overall image quality was comparable, with CS-cine demonstrating acceptable quality and potential superiority in patients with arrhythmias, despite high heterogeneity in arrhythmia subgroups.

Conclusions:

• CS-accelerated cine CMR imaging provides consistent LV characteristic evaluation comparable to Std-cine.
• The image quality of CS-cine is acceptable and may be advantageous for imaging patients with arrhythmias.
• CS-cine represents a viable alternative to Std-cine, potentially improving CMR efficiency and patient experience.