Performance of compressed-sensing cardiac accelerated cine MR in evaluating left ventricular function: a systematic...

To assess the consistency of left ventricular (LV) characteristics on cine cardiac magnetic resonance (CMR) images acquired from compressed-sensing (CS) accelerated cine versus standard segmented cine (Std-cine) sequences, both utilizing a balanced steady-state free precession (bSSFP) readout.

We conducted a systematic review and meta-analysis. Electronic databases were searched for studies where both CS-cine and Std-cine sequences were performed for individual participants and LV characteristic data from the two sequences were reported separately. Two investigators independently assessed the eligibility of the retrieved studies and extracted data. Key outcomes included LV ejection fraction (LVEF), volume, mass, and image quality. We performed subgroup analyses for children, breath control, arrhythmia, and MRI field intensity.

Thirty-five studies were included. The LVEF (%) obtained from CS-cine imaging did not differ from that obtained from Std-cine imaging (standardized mean difference [SMD]: -0.05; 95% confidence interval [95%CI]: -0.11, 0.01; p = 0.12; I² = 0.0%). No other LV parameters differed (I² = 0.0% to 0.0%), nor did heterogeneity differ across subgroups by MR field intensity, breath-hold requirements, children, or arrhythmia (for inter-subgroup heterogeneity, all p < 0.05). The overall image quality was comparable between the two sequences (SMD: -0.36; 95%CI: -0.65, 0.08; p < 0.05; I² = 37%). The difference across participants with arrhythmias (SMD: -0.04; 95%CI: -1.26, 1.18; p = 0.95; I² = 87%) and without arrhythmias (SMD: -0.63; 95%CI: -1.05, -0.21; p = 0.003; I² = 91%) or with no relevant information on arrhythmias (SMD: -0.17; 95%CI: -0.51, 0.18; p = 0.35; I² = 87%) may have accounted for the high heterogeneity.

CS-accelerated cine imaging and standard segmented cine imaging did not differ in their ability to evaluate LV characteristics. The CS-cine images quality was acceptable and superior to that of conventional cine images for arrhythmias.

CRD42022328219.