Improving Striae Distensae With Combined Hyperdiluted Calcium Hydroxylapatite Injection and Fractional Microneedling...

Area of Science:

• Dermatology
• Aesthetic Medicine
• Regenerative Medicine

Background:

• Striae distensae (stretch marks) are common dermal scars with limited effective treatments, especially for chronic types.
• Both Calcium Hydroxylapatite (CaHA) and fractional microneedling radiofrequency (RF) have shown individual regenerative potential.

Purpose of the Study:

• To investigate the safety and efficacy of a combination therapy using hyperdiluted CaHA and fractional microneedling RF for treating striae distensae.
• To assess clinical improvement and patient satisfaction following the combined treatment protocol.

Main Methods:

• A pilot study involving eight female patients with abdominal striae distensae.
• Treatment consisted of one session of hyperdiluted CaHA injection followed by three monthly sessions of RF microneedling.
• Outcomes were evaluated using the Manchester Scar Scale (MSS) and patient satisfaction scores six months post-treatment.

Main Results:

• Significant improvement in mean MSS scores from baseline (14 ± 0.93) to post-treatment (6.88 ± 1.64) (P < .0001).
• High average patient satisfaction score of 8.12 ± 1.72.
• Mild, transient erythema observed in two patients; no serious adverse events reported.

Conclusions:

• The combination of hyperdiluted CaHA and RF microneedling appears to be a safe and effective treatment for striae distensae.
• The therapy yields significant clinical improvements and high patient satisfaction.
• Further larger controlled studies are recommended to validate these findings.